Fatal desquamative interstitial pneumonia in three infants siblings
Identifieur interne : 003601 ( Main/Exploration ); précédent : 003600; suivant : 003602Fatal desquamative interstitial pneumonia in three infants siblings
Auteurs : Asher Tal [Israël] ; Esther Maor [Israël] ; Jacob Bar-Ziv [Israël] ; Rafael Gorodischer [Israël]Source :
- The Journal of Pediatrics [ 0022-3476 ] ; 1984.
English descriptors
- Teeft :
- Alveolar macrophages, Alveolar spaces, Alveolar walls, Alveolitis, Arterial blood, Biopsy, Birth weight, Blood chemistry values, Chest radiograph, Chest radiographs, Chloroquine, Corticosteroid therapy, Cyanosis, Cyclophosphamide, Desquamative, Fatal desquamative, Fibrosing, Fibrosing alveolitis, Foamy cytoplasm, Ground glass appearance, Heart borders, Histologic, Immune complexes, Immunoglobulin values, Interstitial, Interstitial pneumonia, Interstitial pneumonitis, Large clumps, Lung biopsies, Lung biopsy, Lymphoid, Macrophage, Mechanical ventilation, Normal range, Pathologic, Pathologic findings, Pediatrics, Pediatrics june, Pneumonia, Pneumonitis, Radiograph, Rectal temperature, Respiratory failure, Rheumatoid factor, Sibling, Third patient.
Abstract
Desquamative interstitial pneumonia occurred in three siblings. Cough, difficulty in breathing,cyanosis, and failure to gain weight appeared during the first month of life; progressive hypoxia followed, and the three infants died in respiratory failure before the age of 4 months despite intensive drug and supportive treatment. The radiographic and the histologic appearance of the pulmonary changes were similar in all three infants. Chest radiographs yielded normal findings initially, with rapid progression to a ground glass appearance of both lungs. Histologic findings of lung biopsies showed lymphoplasmocytic infiltration and fibrous thickening of the alveolar walls, swelling of alveolar lining cells, and large clumps of macrophages with PAS-positive foamy cytoplasm in the alveolar spaces.
Url:
DOI: 10.1016/S0022-3476(84)80484-9
Affiliations:
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Cough, difficulty in breathing,cyanosis, and failure to gain weight appeared during the first month of life; progressive hypoxia followed, and the three infants died in respiratory failure before the age of 4 months despite intensive drug and supportive treatment. The radiographic and the histologic appearance of the pulmonary changes were similar in all three infants. Chest radiographs yielded normal findings initially, with rapid progression to a ground glass appearance of both lungs. Histologic findings of lung biopsies showed lymphoplasmocytic infiltration and fibrous thickening of the alveolar walls, swelling of alveolar lining cells, and large clumps of macrophages with PAS-positive foamy cytoplasm in the alveolar spaces.</div></front></TEI><affiliations><list><country><li>Israël</li></country></list><tree><country name="Israël"><noRegion><name sortKey="Tal, Asher" sort="Tal, Asher" uniqKey="Tal A" first="Asher" last="Tal">Asher Tal</name></noRegion><name sortKey="Bar Ziv, Jacob" sort="Bar Ziv, Jacob" uniqKey="Bar Ziv J" first="Jacob" last="Bar-Ziv">Jacob Bar-Ziv</name><name sortKey="Gorodischer, Rafael" sort="Gorodischer, Rafael" uniqKey="Gorodischer R" first="Rafael" last="Gorodischer">Rafael Gorodischer</name><name sortKey="Maor, Esther" sort="Maor, Esther" uniqKey="Maor E" first="Esther" last="Maor">Esther Maor</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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